A fluorescence lifetime-based fibre-optic glucose sensor using glucose/galactose-binding protein
نویسندگان
چکیده
منابع مشابه
A fluorescence lifetime-based fibre-optic glucose sensor using glucose/galactose-binding protein.
Alternative, non-electrochemistry-based technologies for continuous glucose monitoring are needed for eventual use in diabetes mellitus. As part of a programme investigating fluorescent glucose sensors, we have developed fibre-optic biosensors using glucose/galactose binding protein (GBP) labelled with the environmentally sensitive fluorophore, Badan. GBP-Badan was attached via an oligohistidin...
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We review progress in our laboratories toward developing in vivo glucose sensors for diabetes that are based on fluorescence labeling of glucose/galactose-binding protein. Measurement strategies have included both monitoring glucose-induced changes in fluorescence resonance energy transfer and labeling with the environmentally sensitive fluorophore, badan. Measuring fluorescence lifetime rather...
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ژورنال
عنوان ژورنال: The Analyst
سال: 2011
ISSN: 0003-2654,1364-5528
DOI: 10.1039/c0an00430h